The awake period lasted from approximately 6:30 AM to 11:00 PM. The patients were hospitalized in the morning (at 7 AM) and stayed for the following 24 hours. The method of recording 24-hour IOP curves has been described in detail. Compared with sitting measurements alone, the collection of supine and sitting office-hour measurements may enhance the correct identification of 24-hour IOP characteristics in both control subjects and untreated patients with glaucoma, thus reducing the need for obtaining 24-hour curves to a minority of patients. It is noteworthy that office-hour measurements did not characterize any 24-hour parameter in 20% of patients with glaucoma.Ĭonclusions. Office-hour sitting measurements correctly identified peak, mean, and IOP fluctuation in 10% of the young adults, 32% of the elderly control subjects, and 20% of the patients with glaucoma, whereas the combination of supine and sitting measurements correctly identified them in 30%, 85%, and 46% of cases, respectively. The percentage of subjects with estimates of all IOP parameters within a cutoff of ☑ (peak and mean) and ☒ mm Hg (fluctuation) was calculated. Peak, mean, and fluctuation of 24-hour IOP curves were compared with office-hour measurements obtained in subjects in the sitting position alone and with combined pressures obtained in the sitting and supine positions (four measurements in each body position from 9 AM to 6 PM).
Measurements were taken at 9 AM 12, 3, 6, and 9 PM and 12, 3, and 6 AM, both in the supine and sitting (Goldmann tonometer) positions. The 24-hour IOP curves of 29 healthy subjects (10 young adults, 19 elderly) and 30 patients with untreated glaucoma were analyzed. To verify whether office-hour measurements in patients in different body positions can estimate the characteristics of 24-hour intraocular pressure (IOP).
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